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Loic Binan

Loic Binan, PhD

Molecular & Regenerative Medicine

Cell neighborhood, Cell-cell interactions, Gene regulatory networks, High throughput CRISPR screens, Human Genetics, Single cell RNA sequencing, Spatial transcriptomics, Sub cellular mRNA localization, Technology development, Time lapse imaging
  • Principal Investigator, Lady Davis Institute for Medical Research
  • Assistant Professor, Department of Human Genetics, McGill University

Contact details

(540) 340-8222 ext. 25251
loic.binan@mcgill.ca

Snapshot

Research in our lab aims to develop technologies to investigate the mechanisms by which gene networks control the self-organization of cells into complex 3-D tissues during development, as well as the modifications to this organization that take place in disease. This includes approaches to collect new types of data as well as algorithms to analyze these data. The techniques we use include gene editing (CRISPR), spatial transcriptomics, single cell RNA sequencing, microscopy, and computational methods for image analysis and statistics. We develop our tools in tissues like the brain or tumors.

Major Research Activities

The specific research areas in the laboratory include:

  • Gene regulatory networks
  • Spatial transcriptomics
  • High throughput genetic screens
  • Cancer
  • Development
  • Bioinformatics

Recent Publications and References

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