Sonia Victoria del Rincon, PhD

Cancer associated fibroblasts, MNK1/2 signalling, Peroxisome, Spatial biology, Tumor microenvironment

sonia.delrincon@mcgill.ca

@delRincon_lab

To come

To come

Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Huang F, Gonçalves C, Bartish M, Rémy-Sarrazin J, Issa ME, Cordeiro B, Guo Q, Emond A, Attias M, Yang W, Plourde D, Su J, Gimeno MG, Zhan Y, Galán A, Rzymski T, Mazan M, Masiejczyk M, Faber J, Khoury E, Benoit A, Gagnon N, Dankort D, Journe F, Ghanem GE, Krawczyk CM, Saragovi HU, Piccirillo CA, Sonenberg N, Topisirovic I, Rudd CE, Miller WH Jr, Del Rincón SV. J Clin Invest. 2021 Apr 15;131(8):e140752. doi: 10.1172/JCI140752.
The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment.
Bartish M, Abraham MJ, Gonçalves C, Larsson O, Rolny C, Del Rincón SV. Nat Rev Cancer. 2023 Jun;23(6):408-425. doi: 10.1038/s41568-023-00567-5. Epub 2023 May 4. PMID: 37142795
Peroxisome disruption alters lipid metabolism and potentiates anti-tumor response with MAPK-targeted therapy in melanoma.
Huang F, Cai F, Dahabieh MS, Gunawardena K, Talebi A, Dehairs J, El-Turk F, Park JY, Li M, Goncalves C, Gagnon N, Su J, LaPierre JH, Gaub P, Joyal JS, Mitchell JJ, Swinnen JV, Miller WH Jr, Del Rincón SV. J Clin Invest. 2023 Aug 24:e166644. doi: 10.1172/JCI166644. Online ahead of print. PMID: 37616051

Researchers